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Joint Pain
There are many forms of arthritis, each of which has a different cause.
Rheumatoid arthritis and psoriatic arthritis are autoimmune diseases in
which the body is attacking itself. Septic arthritis is caused by joint
infection. Gouty arthritis is caused by deposition of uric acid crystals
in the joint that results in subsequent inflammation. Additionally, there
is a less common form of gout that is caused by the formation of needle
shaped crystals of calcium pyrophosphate. This form of gout is known as
pseudogout. trigosamine The most common form of arthritis, osteoarthritis
is also known as degenerative joint disease and occurs following trauma
to the joint, following an infection of the joint or simply as a result
of aging. There is emerging evidence that abnormal anatomy may contribute
to early development of osteoarthritis.
trigosamine
All arthritides feature pain. Patterns of pain differ among the arthridities
and the location. Osteoarthritis is classically worse at night or following
rest. Rheumatoid arthritis is generally worse in the morning and in the
early stages, patients often do not have symptoms following their morning
shower. In elderly people and children, pain may not be the main feature,
and the patient simply moves less (elderly) or refuses to use the affected
limb (children). trigosamine
Elements of the history of the pain (onset, number of joints and which
involved, duration, aggravating and relieving factors) all guide diagnosis.
Physical examination typically confirms diagnosis. Radiographs are often
used to follow progression or assess severity in a more quantitative manner.
trigosamine
Blood tests and X-rays of the affected joints often are performed to
make the diagnosis.
Screening blood tests may be indicated if certain arthridities are suspected.
This may include: rheumatoid factor, antinuclear factor (ANF), extractable
nuclear antigen and specific antibodies. trigosamine
Osteoarthritis (OA, also known as degenerative arthritis or degenerative
joint disease, and sometimes referred to as "arthrosis" or "osteoarthrosis"
or in more colloquial terms "wear and tear"), is a condition
in which low-grade inflammation results in pain in the joints, caused
by wearing of the cartilage that covers and acts as a cushion inside joints.
As the bone surfaces become less well protected by cartilage, trigosamine
the patient experiences pain upon weight bearing, including walking and
standing. Due to decreased movement because of the pain, regional muscles
may atrophy, and ligaments may become more lax. OA is the most common
form of arthritis. The word is derived from the Greek word "osteo",
meaning "of the bone", "arthro", meaning "joint",
and "itis", meaning inflammation, although many sufferers have
little or no inflammation. trigosamine
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